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How to use AI to analyze responses from clinical trial participants survey about informed consent understanding

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Adam Sabla

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Aug 23, 2025

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This article will give you tips on how to analyze responses from a Clinical Trial Participants survey about Informed Consent Understanding, using proven AI survey analysis workflows.

Choosing the right tools for survey data analysis

The approach and tools you use depend on the form and structure of your survey data. Here’s how I think about it:

  • Quantitative data: For questions like “How many participants understood a particular element of informed consent?”—good old Excel or Google Sheets are all you need. Counting responses is quick and straightforward.

  • Qualitative data: When you have open-text answers, or detailed follow-ups (such as “Why did you feel uncertain about the placebo process?”), manual reading gets overwhelming and biased. Here, AI tools are your best friend—able to process, summarize, and highlight patterns at scale.

There are two main approaches when handling qualitative survey responses:

ChatGPT or similar GPT tool for AI analysis

Copy and paste your exported text into ChatGPT, Claude, or another GPT-based AI.

Upside: You can start for free, and simply converse with the AI about your results.

Downside: Managing messy CSV exports, hitting context length limits, and losing structure make this approach cumbersome. You’ll often need to format, chunk, and shepherd the data yourself.

All-in-one tool like Specific

Specific is purpose-built to collect and analyze qualitative survey data from start to finish. When you design your Clinical Trial Participants survey about informed consent understanding here, it will not only automate follow-up questions (to capture richer responses) but also analyze all the data with AI for you.

How it works: The platform automatically applies AI to summarize all answers, extract core themes, and turn raw responses into actionable insights. You get instant, structured analysis—no manual copy-pasting or spreadsheets required. And you can chat directly with the AI about any result, filtering conversations flexibly and drilling down into specific topics.

If you want to see what this looks like in action, check out AI-powered survey response analysis with Specific.

Useful prompts that you can use for Clinical Trial Participants survey response analysis

To get the most insight out of your qualitative data, it’s all about asking AI the right questions—called "prompts"—about your data:

Prompt for core ideas: Use this as your default for large datasets. It’s actually the base prompt used in Specific, but works just as well if you paste it into ChatGPT or other AI tools:

Your task is to extract core ideas in bold (4-5 words per core idea) + up to 2 sentence long explainer.

Output requirements:

- Avoid unnecessary details

- Specify how many people mentioned specific core idea (use numbers, not words), most mentioned on top

- no suggestions

- no indications

Example output:

1. **Core idea text:** explainer text

2. **Core idea text:** explainer text

3. **Core idea text:** explainer text

Give the AI as much context as possible about your survey, what you’re trying to learn, and anything unique about your participants. For example:

These responses are from a survey of clinical trial participants about their understanding of informed consent. My goal is to find where people felt confused or unsure, especially about randomization and placebo. Summarize the most frequent points of confusion and their possible reasons.

For deeper exploration, try: Tell me more about [core idea] — With this, ask the AI to break down any specific insight (like placebo confusion, or voluntary participation).

Prompt for specific topic: Did anyone talk about [randomization]? Include quotes. This helps you quickly validate or bust assumptions about emerging themes in your data.

Prompt for personas: If you want to segment your participants, use:

Based on the survey responses, identify and describe a list of distinct personas—similar to how "personas" are used in product management. For each persona, summarize their key characteristics, motivations, goals, and any relevant quotes or patterns observed.

Prompt for pain points and challenges: Uncover what really troubles participants:

Analyze the survey responses and list the most common pain points, frustrations, or challenges mentioned. Summarize each, and note any patterns or frequency of occurrence.

Prompt for sentiment analysis: Get a read on mood:

Assess the overall sentiment expressed in the survey responses (e.g., positive, negative, neutral). Highlight key phrases or feedback that contribute to each sentiment category.

Prompt for unmet needs & opportunities:

Examine the survey responses to uncover any unmet needs, gaps, or opportunities for improvement as highlighted by respondents.

If you want a ready-to-use generator, check Specific’s Clinical Trial Participants informed consent survey generator or explore template options here.

How Specific structures AI analysis based on question type

Specific’s AI automatically tailors its analysis workflow to how you structured each survey question:


  • Open-ended questions (with or without followups): Summarizes all responses to each question, clearly aggregating followup feedback for a holistic view.

  • Choices with followups: Each answer choice gets its own focused summary, with all related followup replies grouped together—making it easy to see differences in thinking between those who answered “yes” or “no.”

  • NPS questions: The AI breaks down responses by NPS category (detractors, passives, promoters), so you instantly see what different groups appreciated or found confusing about the informed consent process.

You can replicate the same thing manually in ChatGPT—just be prepared for lots of copy-paste, segmenting, and extra work.


Handling AI context limits and large response sets

Strong survey analysis requires fitting all relevant data into the AI’s “context window.” When you have too many Clinical Trial Participants responses, you’ll eventually run into this limit—your AI will stop reading or truncate the data.


I tackle this challenge in two main ways (which Specific automates):

Filtering: Limit the conversations to only those where participants replied to key questions or chose specific answers. That way, AI processes only the most relevant exchanges, keeping things on topic.

Cropping: Choose which questions to send for AI analysis. For example, you may only want to analyze open-text answers to “Did you fully understand the concept of randomization?”—leaving everything else out, fitting more conversations into the AI window.

Read about this feature in detail on Specific’s AI-powered survey response analysis page.

Collaborative features for analyzing Clinical Trial Participants survey responses

Working with a team on survey response analysis—especially on something as nuanced as informed consent understanding in Clinical Trial Participants—is always a challenge. You want to keep everyone aligned, avoid duplicate work, and ensure fresh perspectives get heard.


Chat-driven analysis in Specific: Instead of sending Excel files around, you and your team can chat with the data right inside Specific: pose key questions, refine them collaboratively, and instantly see AI-powered summaries.

Multiple analysis threads: Specific lets you spin up multiple chats, each with its own filters—delving into responses about randomization, voluntary participation, or NPS, for example. Each thread shows the creator, so teammates know who is digging into what angle.

Transparent collaboration: Every message in the shared chat indicates who wrote it, with avatar and name. This makes it easy to track who asked what, follow up, and brainstorm together. You never lose context or repeat analysis, unlike in static report docs.

Check out more collaboration workflows, or learn how to create smarter Clinical Trial surveys with Specific.

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Sources

  1. National Library of Medicine. “Assessment of Understanding of Informed Consent among Participants in a Clinical Trial.”

Adam Sabla - Image Avatar

Adam Sabla

Adam Sabla is an entrepreneur with experience building startups that serve over 1M customers, including Disney, Netflix, and BBC, with a strong passion for automation.

Adam Sabla

Adam Sabla is an entrepreneur with experience building startups that serve over 1M customers, including Disney, Netflix, and BBC, with a strong passion for automation.

Adam Sabla

Adam Sabla is an entrepreneur with experience building startups that serve over 1M customers, including Disney, Netflix, and BBC, with a strong passion for automation.